Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1800 | Thyroid cancer | ICEECE2012

High prevalence of BRAFV600E mutation in the papillary thyroid carcinomas in Korea by peptide nucleic acid clamp real-time PCR

Kim S. , Kim S. , Paik M. , Jeong D. , Jeong Y. , Lee J. , Whangbo Y. , Cho H. , Oh M. , Yang S. , Kim C.

Introduction: Activating somatic mutation of the BRAF gene (V600E) has been identified as the most common genetic event in papillary thyroid carcinoma (PTC) with a variable frequency (32–87%) in various races by different methods.In this study, we report the genetic analysis of BRAF mutation in a Korean cohort of 211 PTC by peptide nucleic acid clamp real-time PCR.Methods: PNA clamp real-time PCR was applied for BRAF analysis ...